Discover the fluid jet mill technology for reducing a powder to a specified particle size distribution.
Micronization by spiral jet mill is a physical process for reducing a powder to a specified particle size distribution. Munit's production sites utilize its own designed MC Jet Mill, fluid jet mill technology for achieving this goal.
The milling process is due to particles with different masses and speeds inside the milling chamber. For example, a particle entering the milling chamber at speed V1 gets a circular movement and is accelerated by the injector nozzles to a higher speed, V2.
When two rotating particles collide at speeds V1 and V2, their kinetic energy breaks them into numerous smaller ones.
The number of particles generated after the collision and their size (namely their mass) depend directly on the kinetic energy accumulated by the two particles before the impact. The particle size can be regulated by controlling the jet's speed and distance between particles before the collision.
Therefore, the parameters controlling the final particle size distribution are:
- Feed Rate (Product amount per unit time): varying the feed rate, particles concentration inside the milling chamber changes; hence distance covered by two particles before the collision can be influenced;
- Pressure: The jet speed changes by varying the fluid pressure through the nozzle section (that remains constant).
The equipment used for micronization consists of the following parts:
- Dosing unit (used to feed the mill with a given quantity of product to be micronized);
- Fluid-jet mill (in which the micronization process itself takes place);
- Cyclone separating filter (where the micronized product and fluid are separated).
These three parts are made of AISI 316 stainless steel; the mill-cyclone filter connecting hose is made of food-grade polyresin; the filtering sleeves on the centrifugal separating filter are made of antistatic polyester. Both the connecting hose and the filter bag are dedicated.
How it works
MC Spiral Jet Mills
MC Spiral Jet Mills use a process gas stream to reduce particle size through particle-particle collision. With no mechanical milling parts, they are versatile and usable at different temperatures.
- Size reduction by particle-particle collision within the process gas stream
- No mechanical moving milling parts
- Usable at different temperatures
Top Benefits of Using Jet Milling Technology for Particle Size Micronization
Spiral jet mills offer several advantages versus traditional milling techniques, including precise control over particle size distribution, reduced contamination risk, and high yields. They can also process heat-sensitive materials and are easy to clean and maintain.
- Very fine powder down to 1 micron
- Achieved yields higher than 99%
- Reduced product build-up
- Precise scalability guaranteed
- Easy cleaning
Range of Application
- Pharmaceutical industry
- Oral dosage form
- Inhalation powders (MDI and DPI)
- Transdermal drug delivery
- Oncological solid dosage form
- Opthalmic dosage form
- New Chemical Entities, R & D
- Food industry