Resolve post-micronization issues and enhance the quality of pharmaceutical products.

At Munit, we offer Product Conditioning Services to minimize the amorphous content and to improve the flowability and stability of micronized powder designated for inhalation delivery form, such as Dry Powder Inhaler (DPI).

The Post Milling Conditioning Process is intended to facilitate a quick and controlled reconversion of particles from an amorphous state generated during the high-energy micronization process back to their crystalline form. This reconversion helps enhance the micronized powder's flowability and stability. In addition, our team can perform the conditioning process for standard Active Pharmaceutical Ingredients (API) and High Potency Active Pharmaceutical Ingredients (HPAPI).

Our conditioning is performed inside a ventilated chamber / isolator with controlled temperature and humidity for a defined time. We use Dynamic Vapour Sorption (DVS) to measure the amorphous content and in partnership with external Labs we offer other suitable analytical techniques.

At Munit, we adhere to the highest standards of quality and safety. Our Product Conditioning Services are performed under GMP guidelines.

Contact us to learn more about how we can support your micronization processes and enhance the quality and stability of your micronized powders.

How it works

How the Postmilling Conditioning works

Postmilling conditioning is carried out placing the powder on trays, controlling the temperature and humidity, and allowing the particles to relax. This process facilitates the controlled conversion of amorphous particles back into their original crystalline form, ultimately enhancing the product's stability.

  • The powder is placed on trays
  • Controlled temperature and humidity
  • Defined time for relaxation of the particles
  • Controlled conversion of the amorphous particles back into their originally crystalline form


Enhancing Product Quality with Postmilling Conditioning

Postmilling conditioning can improve the particle size distribution and flow properties of pharmaceutical products, ultimately enhancing their quality and consistency.

  • Resolve potential post micronization polymorphism issues
  • Reduce agglomeration


Range of Application for very fine powders

  • Pharmaceutical industry
  • Oral dosage form
  • Inhalation powders (MDI and DPI)
  • Transdermal drug delivery
  • Oncological solid dosage form
  • Opthalmic dosage form
  • New Chemical Entities, R & D

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We are world leading player in the field of particle size engineering for pharmaceutical substances.

Range of Products

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Start a project with us

Find out how Munit can help you to increase the bioavailability of your pharmaceutical substances by reducing their particle size.

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